SEER Training Modules
11/27/12 - The NCI is working on updating materials.
Biopsy Example
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Name: Sammy Kidd
Hospital No.: 0000037
Sex: Male
Age: 56
Race: White
Clinical Diagnosis: Carcinoma of Bladder
Address: _______________________________
Path No.: S91-1017
Clinic or Floor:___________________________
Surgery Date: 03/31/91
Pathologic Diagnosis: Papillary transitional cell carcinoma, GR III
Operation: Multiple biopsies of bladder
Attending Physician: O.P. Bixby, MD
Gross:
The specimen is submitted in formalin in two parts.
Part one is labeled "random bladder biopsy" and consists of two fragments of tissue each measuring approximately 1 x 1 mm.
Part two is labeled "right anterior bladder wall" and consists of multiple fragments of tissue measuring from 1 x 0.5 x 0.5 cm to 2 x 1 x 0.5 cm. This tissue is dark and appears to have hyperplastic epithelium and underlying muscularity.
Microscopic:
Sections of random bladder biopsies show mild to moderate epithelial atypia. Sections of urinary bladder labeled "right anterior bladder wall" show a papillary neoplasm with markedly atypical cells and high mitotic activity invading in solid nests into the lamina propria, but not the muscularis. Adjacent mucosa shows severe atypia.
Diagnosis:
Urinary bladder (biopsy) - Papillary transitional cell carcinoma, Grade III.
Urinary bladder (random biopsies) - Mild to moderate epithelial atypia.
Ralph Abitt, MD
Pathologist
