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Rule B. If a topographic site
is modified by a prefix such as peri-, para-, or the like,
and is not specifically listed in ICD-O-3, code to the appropriate
ill-defined subcategory C76 (ill-defined site), unless the
type of tumor indicates origin from a particular tissue.
The prefixes peri-, para-, pre-, supra-, and others are often
used with topographic sites and various organs of the body.
A few topographic sites modified by such prefixes are listed
in ICD-O and given specific code numbers. For example, "periadrenal
tissue," "peripancreatic tissue," and "retrocecal
tissue" are listed and given the code number C48.0 which
is "retroperitoneum." "Para-aortic lymph node"
is listed in ICD-O and given the same code number, C77.2,
as "aortic lymph node." It is not possible to list
all topographic sites that might be modified by these prefixes
in ICD-O. In practice, use of such prefixes indicates that
the topographic site is ill-defined. Coders should use the
C76 rubric for other ill-defined sites not listed in ICD-O.
This same rule applies to other imprecise designations such
as "in the area of" or "in the region of"
a specific topographic site.
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