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T (TUMOR SIZE)
TX Minimum requirements to assess the primary tumor cannot
be met
T0 No evidence of primary tumor
TIS Carcinoma in situ
T1, T2, T3, T4 Progressive increase in tumor size or involvement
T CATEGORIES
I. HOLLOW ORGANS
Depth of invasion through wall of organ. Usually includes
terms like submucosa, muscularis, and wall. T4 usually lists
adjacent structures. Requires pathologic assessment of tumor
to determine depth of invasion.
1. Esophagus
2. Stomach
3. Small Intestine
4. Colon/Rectum
5. Gallbladder, bile ducts
6. Ampulla of Vater
7. Corpus uteri
8. Penis
9. Bladder
10. Renal pelvis, Ureter, Urethra
11. Fallopian Fube
Also: Malignant Melanoma
II. PARENCHYMAL AND OTHER ORGANS
A. Size of primary tumor. Involves measuring the primary
clinically or pathologically. Sometimes involves counting
the number of tumors or nodules. T3 and T4 usually list adjacent
structures.
- Lip and oral cavity
- Oropharynx
- Salivary glands
- Thyroid (stage grouping also requires histology and age
of patient)
- Anus and anal canal
- Liver
- Sarcoma (stage grouping based primarily on grade of tumor)
- Skin (basal and squamous cell)
- Breast
- Kidney
- Brain (no scheme available in TNM)
- Eyelid (carcinoma)
- Conjunctiva
- Uvea (Choroid, Ciliary Body, and Iris)
- Retina
- Orbit (sarcoma)
- Lacrimal gland
- Wilms'
Tumor
- Neuroblastoma
B. Location of tumor and extension of primary. Requires knowledge
of relationship of anatomic structures in and near the primary.
Can be clinical or pathological.
- Hypopharynx, nasopharynx
- Larynx
- Paranasal sinus
- Pancreas
- Lung
- Pleural mesothelioma
- Bone
- Cervix uteri
- Ovary
- Vagina, Vulva
- Prostate
- Testis
- Malignant lymphoma and Hodgkin's disease
- Conjunctiva (melanoma)
- Retinoblastoma
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