 |
 |
Back to Morphology and Grade | || Go to Leukemia || | |||||||||
|
||||||||||||
| Rappaport
and Lukes-Collins Classification | | Kiel
Classification | Working
Formulation | REAL Classification | WHO Classification | |
||||||||||||
|
|
Back to Morphology and Grade | || Go to Leukemia || | |||||||||
|
||||||||||||
| Rappaport
and Lukes-Collins Classification | | Kiel
Classification | Working
Formulation | REAL Classification | WHO Classification | |
||||||||||||
Developed by Lukes and Butler; modified and presented at a conference in Rye, New York in 1966. This system found that the different cellular subtypes had different prognoses:
| Most favorable | Lymphocyte predominant | 96513 (NOS), 96583 (diffuse), 96513 (nodular) |
| Favorable | Nodular sclerosis |
96633 (NOS), 96643 (cellular phase) also: 96653 (HD NS, lymphocyte predominance) 96653 (HD NS mixed cellularity), 96673 (HD NS, lymphocytic depletion) |
| Guarded | Mixed cellularity | 96523 (NOS) |
| Least favorable | Lymphocyte depletion | 96533 (NOS) 96543 (diffuse fibrosis), 96553 (reticular) |
Reed-Sternberg cells are diagnostic of Hodgkin's disease because of their
specific morphologic characteristics.
