Lymphoma Staging Scheme
The Ann Arbor staging classification is commonly used for the staging of lymphomas and is the scheme defined in the AJCC Manual for Staging Cancer. Originally developed for Hodgkin disease, this staging scheme was later expanded to include non-Hodgkin lymphoma.
Staging of Lymphoma: Ann Arbor classification
Involvement of two or more lymph node regions on the same side of the diaphragm (II) or localised involvement of extra-lymphatic organ or site and of one or more lymph node regions on the same side of the diaphragm (IIE).
Involvement of lymph node regions on both sides of the diaphragm (III) which may also be accompanied by localised involvement of extralymphatic organ or site (IIIE) or by involvement of the spleen (IIIS) or both (IIISE)