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Head & Neck Staging: Table Three

Larynx (C32.0, C32.1, C32.2, C10.1)
TNM Classification Histological/Clinical Features
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
Tis Carcinoma in situ
Supraglottis
TNM Classification Histological/Clinical Features
T1 Limited to one sub site, with normal vocal cord mobility
T2 Invades mucosa of > one adjacent sub site of supraglottis or glottis or region outside the supraglottis; without fixation of larynx
T3 Limited to larynx with vocal cord fixation and/or or invades postcricoid area, pre-epiglottic tissues, paraglottic space, and/or minor thyroid cartilage erosion.
T4a Invades through thyroid cartilage and/or tissues beyond larynx
T4b Invades prevertebral space, encases carotid artery, or invades mediastinal structures
Glottis
TNM Classification Histological/Clinical Features
T1 Limited to vocal cord(s), with normal mobility
T1a Limited to one vocal cord
T1b Involves both vocal cords
T2 Extends to supraglottis, and/or subglottis, and/or with impaired cord mobility
T3 Limited to larynx with vocal cord fixationT4 = Invades thru thyroid cartilage and/or other tissues beyond larynx
T4a Invades through thyroid cartilage and/or tissues beyond larynx
T4b Invades prevertebral space, encases carotid artery, or invades mediastinal structures
Subglottis
TNM Classification Histological/Clinical Features
T1 Limited to subglottis
T2 Extends to vocal cord(s) with normal/impaired mobility
T3 Limited to larynx with vocal cord fixation
T4a Invades cricoid or thyroid cartilage and/or tissues beyond larynx
T4b Invades prevertebral space, encases carotid artery, or invades mediastinal structures