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Head & Neck Staging: Table Two

Pharynx (C01, C05.1, C09, C10.0, C10.2, C10.3, C11-C13)
TNM Classification Histological/Clinical Features
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
Tis Carcinoma in situ
Oropharynx
TNM Classification Histological/Clinical Features
T1 2 cm or less
T2 > 2 but < 4 cm
T3 > 4 cm
T4 Invades adjacent structures
T4a Invades larynx, deep/extrinsic muscle of tongue, medial pterygoid, hard palate, or mandible
T4b Invades lateral pterygoid muscle, pterygoid plates, lateral nasopharynx, or skull base or encases carotid artery
Hypopharynx
TNM Classification Histological/Clinical Features
T1 Limited to one sub site of hypopharynx and 2cm or <
T2 > 2 but < 4 cm without fixation or more than one sub site or adjacent site
T3 > 4 cm or with hemilarynx fixation
T4a Invades thyroid/cricoid cartilage, hyoid bone, thyroid gland, esophagus, or central compartment soft tissue
T4b Invades prevertebral fascia, encases carotid artery, or involves mediastinal structures
Nasopharynx
TNM Classification Histological/Clinical Features
T1 Confined to nasopharynx
T2 Extends to soft tissue of oropharynx and/or nasal fossa
T2a Without parapharyngeal extension
T2b With parapharyngeal extension
T3 Invades bony structures and/or paranasal sinuses
T4 Intracranial extension, and/or involvement of cranial nerves, infratemporal fossa, hypopharynx, or orbit