Cell type, percent of cells in blast phase
Pleural effusion (thoracentesis) or ascites (paracentesis)
Bone Marrow Biopsy
Also called bone marrow aspiration. Aspiration of bone marrow cells to determine involvement by tumor. This procedure is used to diagnose leukemia. Bilateral bone marrow biopsies and aspirations should be done for accurate assessment of blast content.
The presence of malignant cells in the bone marrow with a normal or leukopenic count in the circulating blood.
Abnormal cytoplasmic granules which distinguish AML from ALL.
Cells in an immature stage of cellular development; also called stem cells.
For chronic leukemia, increased blast cells inthe peripheral blood accompanied by progressive splenomegaly and fever
Abnormal increase in the number of cells; leukocytosis (increased white cells); thrombocytosis (increased thrombocytes or platelets)
Leukemic involvement of the lungs or central nervous system characterized by thickening or "sludging" of blood vessels due to the increased number of cells in the blood.
Abnormal decrease in the number of cells; leukocytopenia (decreased white cells); thrombocytopenia (decreased platelets); neutropenia (decreased granulocytes); pancytopenia (decrease in all types of cells).
Large cell lymphoma which develops after treatment for CLL treatment-induced acute leukemia—a second, acute leukemia that develops after chemotherapy for chronic leukemia.
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