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SEER Training Modules
11/27/12 - The NCI is working on updating materials.

Staging

The TNM staging system parallels the American Urologic System staging.

Prostate Cancer Staging (Abridged Version)

AJCC Jewett Definition
T0 No evidence of primary
T1 A Clinically inapparent
T2 B Confined to prostate gland
T3 C Through the capsule
T4 Fixed; adjacent structures
N_, M_ D Distant metastases

Criteria for TNM Clinical Staging: Physical examination including digital examination, histologic verification of malignancy, imaging, endoscopy, laboratory tests.

Criteria for TNM Pathologic Staging: total removal of the prostate and seminal vesicles as well as pelvic lymph node dissection is required for pathologic staging.

Brief Summaries of 6th Edition Categories

TNM Classification Histological/Clinical Features
T1 T1 Not palpable or visible
T1a <=5%
T1b >5%
T1c Diagnosed on needle biopsy only
T2 T2 Confined to prostate
T2a One-half of one lobe or less
T2b >one-half of one lobe but not both lobes
T2c Both lobes
T3 T3 Through prostatic capsule
T3a Extracapsular
T3b Seminal vesicles(s)
T4 Fixed or invading adjacent structures: bladder neck, external sphincter, rectum, levator muscles, pelvic wall
N1 Regional lymph node(s)
M1a Non-regional lymph nodes(s)
M1b Bone(s)
M1c Other site(s)

Collaborative Stage Elements

For more details on Collaborative Stage, see the Intro to Collaborative Staging module.