Grade

Grade is collected in 4 data items

Data Item	Date Item #	Text Field #	Comments
Grade Clinical	3843	2570: Text-Dx Proc Path	Information obtained from biopsy
Grade Pathological	3844	2570: Text-Dx Proc Path	Information obtained from surgical resection
Grade Post Therapy Clinical	1068	2570: Text-Dx Proc Path	Information obtained from a bx or FNA after neoadjuvant therapy but prior to post neoadjuvant surgical resection
Grade Post Therapy Pathological	3845	2570: Text-Dx Proc Path	Information obtained from post neoadjuvant surgical resection

See Schemas | SSDI Data | (naaccr.org) (includes general instructions for Grade) or SEER*RSA (cancer.gov) for complete coding instructions for these data items.

The grading of colorectal tumors is based on a 4-grade Nuclear grading system.

Grade is to be coded from the original tumor. Do not use grade information from lymph nodes, metastatic tissue, or recurrences.

Grade definitions for Colorectal
Code	Grade Description
1	G1: Well differentiated
2	G2: Moderately differentiated
3	G3: Poorly differentiated
4	G4: Undifferentiated, anaplastic
9	Grade cannot be assessed (GX); Unknown

For further information on coding grade for Colorectal, see the Grade Manual, Grade ID: 02

Grade manual can be found at Schemas | SSDI Data

Updated: June 24, 2025