Incidence and Mortality

Worldwide, colorectal cancer is the third most common form of cancer. In 2022, there were an estimated 1.93 million new cases of colorectal cancer and 903,859 deaths.

Estimated new cases and deaths from colon and rectal cancer in the United States in 2025.

• New cases of colon cancer: 107,320.
• New cases of rectal cancer: 46,950.
• Deaths: 52,900 (colon and rectal cancers combined).

For more information on Incidence and Mortality for Colorectal cancer, see:

• National Cancer Institute: Cancer Statistics Explorer Network
  • This link will provide you with statistics for Colorectal cancer. Statistics include incidence by age, race, stage, and also survival
  • Colorectal Cancer Information | Understanding Colorectal Cancer | American Cancer Society

Colon cancer is highly treatable and often curable disease when localized to the bowel. Surgery is the primary form of treatment and results in cure in approximately 50% of patients. However, recurrence following surgery is a major problem for non-localized disease and is often the ultimate cause of death.

Updated: June 24, 2025