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Signs & Symptoms

Endometrial Cancer

  • Abnormal vaginal bleeding (90%)
    • Post-menopausal bleeding more than one year after last period
    • Premenopausal bleeding
      • Irregular menses, prolonged menses, intermenstrual bleeding, excessive menstrual bleeding
  • Abnormal Pap smear
  • Advanced disease
    • Ascites
    • Jaundice (yellowing of the skin and eyes due to biliary obstruction)
    • Bowel obstruction from abdominal metastases
    • Respiratory distress from lung metastases

Placental Cancer

  • Vaginal spotting, bleeding
  • Abnormal discharge, e.g., passage of villi (cystic grape-like clusters)
  • Lower abdominal pain
  • Nausea and/or vomiting
  • Abnormal nipple discharge
  • Swelling of the lower abdomen due to enlarged uterus
  • Uterus that does not decrease in size after pregnancy
  • Absent fetal heart tones