Morphology & Grade
ICD-O-3 Morphology Codes
If the diagnostic term in the pathology report is not in the list below, be sure to consult your ICD-O-3 manual.
60% of testicular cancers will show a single cell type; the remainder will show mixed cell types.
Germ cell tumors (germinoma, 90643; germ cell tumor, nonseminomatous, 90653)
- Seminoma (90613, 90623, 90663; most common 40-50%; slow to spread; more likely to occur in older patients; highly radiosensitive; good prognosis)
- Non-Seminoma (teratoma and embryonal carcinoma comprise 50% of all testicular cancers)
- Teratoma (90803, 90823, 90833)
- Malignant trophoblastic teratoma (91023)
- Embryonal carcinoma (90703; also called embryonal cell carcinoma—poorer prognosis)
- Teratocarcinoma (90813; a combination of teratoma and embryonal carcinoma; may metastasize as embryonal or teratocarcinoma)
- Yolk sac tumor (90713; also called endodermal sinus tumor, infantile embryonal carcinoma; common under the age of 15)
- Choriocarcinoma (91003; rare < 0.5%; aggressive; metastasize only as choriocarcinomas)
- Choriocarcinoma with other germ cell elements (91013)
Note: seminoma mixed with non-seminoma should be considered non-seminoma for treatment decisions.
Less than 5% of testicular cancers (not included in testicular staging)
- Non-germinal tumors
Arise from testicular mesodermal tissue; rare as malignancies
- Leydig cell tumor (86503)
- Sertoli cell tumor (86403)
Most common in men over 60 years old
- Rhabdomyosarcoma (rare)