Grade

Grade is collected in 4 data items.
Data Item Data Item # Text Field # Comments
Grade Clinical 3843 2570: Text-Dx Proc Path Information obtained from initial workup (FNA, TURB, biopsy) prior to treatment
Grade Pathological 3844 2570: Text-Dx Proc Path Information obtained from surgical resection
Grade Post Therapy Clinical 1068 2570: Text-Dx Proc Path Information obtained after neoadjuvant therapy (biopsy, FNA) and prior to post neoadjuvant surgical resection
Grade Post Therapy Pathological 3845 2570: Text-Dx Proc Path Information obtained from post neoadjuvant surgical resection

See Schemas | SSDI Data | (naaccr.org)External Website Policy (includes general instructions for Grade) or SEER*RSA (cancer.gov) for complete coding instructions for these data items.

The grading of urothelial (transitional) tumors is based on the WHO Classification, which is a two-grade system. These histologies are either low-grade (L) or high-grade (H). Although the low-grade and high-grade are part of the histology name, the low and high can be used for assigning grade.

For the non-transitional histologies (i.e., squamous cell carcinoma, adenocarcinoma), these use a three-grade system. This three-grade system is based on the nuclear grading system.

  • Well differentiated
  • Moderately differentiated
  • Poorly differentiated, undifferentiated, anaplastic

Grade is to be coded from the original tumor. Do not use grade information from lymph nodes, metastatic tissue, or recurrences.

Grade Definitions for Bladder
Code Description
1 G1: Well differentiated
2 G2: Moderately differentiated
3 G3: Poorly differentiated
L LG: Low-grade
H HG: High-grade
9 Grade cannot be assessed (GX); Unknown

For further information on coding grade for Bladder, see the Grade Manual, Grade ID: 19.

Grade manual can be found at Schemas | SSDI DataExternal Website Policy

Updated: April 22, 2025