Immunotherapy

See the current version of the SEER Program Coding Manual under Reporting Guidelines, Section VII: First Course of Therapy, for complete coding instructions for the immunotherapy data items.

Immunotherapy or biologic response modifiers (BRM) helps a person’s immune system fight cancer. These drugs work in more than one way to kill cancer cells. They are also called targeted therapy because they target specific changes or substances in cancer cells.

• Targeted therapy uses drugs or other substances to block the action of specific enzymes, proteins, or other molecules involved in the growth and spread of cancer cells.

Immunotherapy is used more in treatment for recurrent prostate cancer.

Document immunotherapy details in NAACCR Item #2660: Text-BRM.

Updated: June 15, 2026