Morphology & Grade
ICD-O-3 Morphology Codes
Transitional cell carcinoma
81203; most common morphology
Squamous cell carcinoma (80703)
Occurs in 8% of all bladder carcinomas.
Adenocarcinoma (81403) of the bladder
Sessile (flat or attached by a broad base)
Infiltrating type; spread widely through the bladder wall and surrounding structures; less gross tumor formation in the bladder lumen.
Most bladder tumors; will often occur and recur in multiple sites within the bladder. Papillary carcinomas are more frequently single, firmer, have broader stalk than benign tumors and form large, bulky, cauliflower-like growths.
Synonyms for /2 behavior (carcinoma in situ, intraepithelial, noninfiltrating, noninvasive): CIS, Stage 0, confined to epithelium, intraepithelial, involvement up to but not including the basement membrane, noninfiltrating, noninvasive, no stromal involvement, papillary noninfiltrating, noninvasive papillary, and, uniquely for bladder, stage "Ta".