Head & Neck Staging: Table Three
| TNM Classification | Histological/Clinical Features | 
|---|---|
| TX | Primary tumor cannot be assessed | 
| T0 | No evidence of primary tumor | 
| Tis | Carcinoma in situ | 
| TNM Classification | Histological/Clinical Features | 
|---|---|
| T1 | Limited to one sub site, with normal vocal cord mobility | 
| T2 | Invades mucosa of > one adjacent sub site of supraglottis or glottis or region outside the supraglottis; without fixation of larynx | 
| T3 | Limited to larynx with vocal cord fixation and/or or invades postcricoid area, pre-epiglottic tissues, paraglottic space, and/or minor thyroid cartilage erosion. | 
| T4a | Invades through thyroid cartilage and/or tissues beyond larynx | 
| T4b | Invades prevertebral space, encases carotid artery, or invades mediastinal structures | 
| TNM Classification | Histological/Clinical Features | 
|---|---|
| T1 | Limited to vocal cord(s), with normal mobility | 
| T1a | Limited to one vocal cord | 
| T1b | Involves both vocal cords | 
| T2 | Extends to supraglottis, and/or subglottis, and/or with impaired cord mobility | 
| T3 | Limited to larynx with vocal cord fixationT4 = Invades thru thyroid cartilage and/or other tissues beyond larynx | 
| T4a | Invades through thyroid cartilage and/or tissues beyond larynx | 
| T4b | Invades prevertebral space, encases carotid artery, or invades mediastinal structures | 
| TNM Classification | Histological/Clinical Features | 
|---|---|
| T1 | Limited to subglottis | 
| T2 | Extends to vocal cord(s) with normal/impaired mobility | 
| T3 | Limited to larynx with vocal cord fixation | 
| T4a | Invades cricoid or thyroid cartilage and/or tissues beyond larynx | 
| T4b | Invades prevertebral space, encases carotid artery, or invades mediastinal structures | 
 An official website of the United States government
 An official website of the United States government