Other Therapies

Systemic Therapy

Under clinical investigation for treatment of various head and neck cancers is Isoretinoin (Retin-A). Used daily for a year, it may prevent development of subsequent primaries.

Key words

Neoadjuvant chemotherapy
Chemotherapy administered prior to surgery or radiation therapy, intended to shrink tumor mass and make it more treatable by another modality.

Chemotherapy agents used alone or in combinations:

• Cisplatin
• 5-FU
• Bleomycin
• Methotrexate
• Doxorubicin (adriamycin)
• Cyclophosphamide

Biological Response Modifiers

Interferon