Signs & Symptoms
Many are "silent" tumors—no pain or other symptoms until tumors reach advanced stages.
Cervical lymph node metastases at the time of diagnosis (70% for pyriform sinus, 40% for postcricoid, 50% for posterior hypopharynx, 75% for nasopharynx, 70% for tonsil and base of tongue, 30-65% of soft palate and pharyngeal wall, depending on the size of the primary).
Pain, sore throat, dysphagia, pain radiating to the ear; asymptomatic mass in neck, hemoptysis.
Odynophagia, referred otalgia, dysphagia; hoarseness; hemoptysis.
Asymptomatic swelling; occasionally painful mass.
Paranasal sinuses and nasal cavity
Early stages are asymptomatic; advanced stages develop dull face or tooth pain, loose teeth, nasal obstruction, rhinorrhea, nosebleeds, and other symptoms.
Plummer-Vinson syndrome (achlorhydria, sideropenic anemia, atrophy of the mucous membranes of the mouth, pharynx, and esophagus)
Associated with oral cavity and hypopharynx cancers.