Case Example 7 (Primary Site and Histology)

Patient presents with palpable cervical lymphadenopathy. An MRI of the Head and Neck is done showing extensive cervical lymphadenopathy. PET scan ordered showing lymph nodes above and below the diaphragm. Biopsy diagnosis is diffuse large B-cell lymphoma (DLBCL). Bone marrow done which is positive for DLBCL.

Involvement Comments
Lymph nodes Cervical lymphadenopathy, lymph nodes above and below the diaphragm
Organ involvement None
Common metastatic sites Bone marrow

Coding of the case (Lymphoma schema)

Data Item Coding
M Rule M2. Single histology
PH Rule PH21: Multiple lymph nodes
Primary site C778: Multiple lymph node regions
Histology 9680/3: DLBCL
Diagnostic confirmation 1 (positive histology)
EOD Primary Tumor 800 (due to positive bone marrow)
EOD Regional Nodes 888 (not applicable)
EOD Mets 88 (not applicable)
Summary Stage 7 (distant due to positive bone marrow)
Mets at Dx Data Items (all 6) Mets at Dx Other: 1 (bone marrow), Mets at Dx-Distant lymph nodes: 8, remaining Mets at Dx data items: 0

Updated: December 2, 2025