The TNM staging system parallels the American Urologic System staging.
Prostate Cancer Staging (Abridged Version)
|T0||No evidence of primary|
|T2||B||Confined to prostate gland|
|T3||C||Through the capsule|
|T4||Fixed; adjacent structures|
|N_, M_||D||Distant metastases|
Criteria for TNM Clinical Staging: Physical examination including digital examination, histologic verification of malignancy, imaging, endoscopy, laboratory tests.
Criteria for TNM Pathologic Staging: total removal of the prostate and seminal vesicles as well as pelvic lymph node dissection is required for pathologic staging.
Brief Summaries of 6th Edition Categories
|TNM Classification||Histological/Clinical Features|
|T1||T1||Not palpable or visible|
|T1c||Diagnosed on needle biopsy only|
|T2||T2||Confined to prostate|
|T2a||One-half of one lobe or less|
|T2b||>one-half of one lobe but not both lobes|
|T3||T3||Through prostatic capsule|
|T4||Fixed or invading adjacent structures: bladder neck, external sphincter, rectum, levator muscles, pelvic wall|
|N1||Regional lymph node(s)|
|M1a||Non-regional lymph nodes(s)|
Collaborative Stage Elements
For more details on Collaborative Stage, see the Intro to Collaborative Staging module.