Morphology & Grade

If the diagnostic term in the pathology report is not in the list below, be sure to consult your ICD-O manual.


  • Adenocarcinoma (814_3 ; most common malignancy of the endometrium —75% of all cases)
  • Clear cell carcinoma (83103; 1% of all cases)
  • Papillary serous carcinoma (84603; 6% of all cases)
  • Adenoacanthoma (85703; adenocarcinoma with a squamous component)
  • Adenosquamous carcinoma (85603; mixed adenocarcinoma and squamous carcinoma; 18% of all cases)
  • Sarcomas arise from the myometrium
  • Leiomyosarcoma (88903, 88913)
  • Mixed Mullerian sarcoma (89503)

Synonyms for in situ carcinoma: Bowen's disease, Stage 0, CIN grade III, confined to epithelium, intraepithelial, involvement up to but not including the basement membrane, noninfiltrating, noninvasive, no stromal involvement, papillary noninfiltrating

Key words
Atypical ad enomato us hyperplasia—a benign condition which is regarded by some as a precursor to endometrial carcinoma


Hydatidiform mole (91000; products of conception that lack an intact fetus with gross cyst-like swelling of chorionic villi)

Choriocarcinoma (91003; highly malignant gestational trophoblastic neoplasms occuring in a hydatidiform mole)

Chorioadenoma destruens (91001; locally invasive; rarely metastatic)
Placental-site trophoblastic tumor (91041; rare tumor arising from placental implantation site with infiltration of myometrium)