Lymphoma Ocular Adnexa

This Hematopoietic schema is for select lymphoma histologies that occur within specific subsites of the eye, including skin of the eyelid. Historically these lymphomas have been included in the general lymphoma grouping.

Staging is based on whether the conjunctiva, orbit and eyelid are involved. Lymph nodes are evaluated based on where they are located and distant metastasis is based on non-contiguous involvement of tissues or organs outside of the eye.

Other eye lymphomas (C691-C694, C698-C699) will be coded in the Lymphoma schema.

Grade is applicable for follicular lymphomas (9690, 9691, 9695, 9698) only. See Table 23 in the Grade manual for further instructions on how to code grade for this schema.

Data Item Criteria/Comments
Histologies

9590-9699, 9702-9719, 9725-9726, 9734-9738, 9823, 9826-9827, 9930
Primary Sites

C441, C690, C695-C696
EOD Primary Tumor

Conjunctiva involved without eyelid or orbital involvement

Orbit involved with or without conjunctiva

Preseptal eyelid involvement with or without orbit or conjunctive

Extension into bone, brain, maxillofacial sinuses
EOD Regional Nodes

Single lymph node superior to the mediastinum

Multiple lymph nodes superior to the mediastinum

Mediastinal lymph nodes

Peripheral central lymph node involvement (diffuse or disseminated)

Distant lymph nodes
EOD Mets

Noncontiguous involvement of tissue or organs outside ocular adnexa

Blood/peripheral blood/bone marrow
Summary Stage

Code 1: Conjunctiva, orbital or preseptal eyelid involvement

Code 2: Bone, brain, and maxillofacial involvement

Code 3: Conjunctiva, orbital or preseptal eyelid involvement and lymph nodes

Code 4: Bone, brain, and maxillofacial involvement and lymph nodes

Code 7: Non-contiguous involvement of tissue or organs outside ocular adnexa, blood/peripheral blood, bone marrow, distant lymph nodes
Grade

Grade is applicable for the follicular lymphomas: 9690, 9691, 9695, 9698

Updated: December 2, 2025