Incidence and Mortality
Hematopoietic Neoplasms are divided into several major groups. Below are the incidence and death cases per year for the most common groupings.
| Histology(ies) | Incidence (per year) | Deaths (per year) |
|---|---|---|
| Acute lymphoblastic leukemia | 6,100 | 1,400 |
| Acute myeloid Leukemia | 22,010 | 11,090 |
| B-cell non-Hodgkin lymphoma | 80,350 | 19,390 |
| Chronic lymphocytic leukemia | 23,690 | 4,460 |
| Chronic myeloid leukemia | 9,560 | 1,290 |
| Hodgkin lymphoma | 8,720 | 1,150 |
For more information on Incidence and Mortality for Hematopoietic cancers, see:
- National Cancer Institute: Cancer Statistics Explorer Network
- This link will provide you with statistics for leukemia, non-Hodgkin lymphoma, Hodgkin lymphoma, chronic myeloproliferative disorders, and myelodysplastic syndromes. Statistics include incidence by age, race, stage, and survival.
- Blood Cancer | American Cancer Society

Treatments for Hematopoietic neoplasms have improved greatly over the last 40 years. Survival rates have increased, especially for children with ALL. For some Hematopoietic neoplasms, recurrence following remission is a major problem and is often the ultimate cause of death.
Risk Factors
All cancers have risk factors. These risk factors are not collected as data items in the registry field but should be documented in the text fields in the abstract.
Per the NCI Dictionary, risk factors are something that increases the chance of developing a disease. Some examples of risk factors for cancer are age, a family history of different types of cancers, use of tobacco products, exposure to radiation or certain chemicals, infection with specific viruses or bacteria, and even genetic changes.
For more general information about Risk Factors, see Risk Factors for Cancer, or for specific information on risk factors for Hematopoietic neoplasms, see Leukemia—Health Professional Version - NCI or Lymphoma—Health Professional Version - NCI
Updated: December 2, 2025