Current therapy for Hodgkin lymphoma cures over 75% of patients. Standards of treatment are radiation therapy and combination chemotherapy.

Treatment for non-Hodgkin lymphoma depends on the cell type and stage at diagnosis. Treatment for both Hodgkin lymphoma and non-Hodgkin lymphoma is usually radiation therapy (for early stage disease, Stage I and II) and/or chemotherapy (for stage III and IV cases), but this may vary by cell type. For example, low grade, low stage non-Hodgkin lymphoma may be treated with radiation only, whereas intermediate grade, low stage NHL should receive radiation and chemotherapy, and high-grade, low stage NHL would probably receive chemotherapy only.

Lymphomas, particularly NHL can convert to a more aggressive form after initial treatment.

Low grade non-Hodgkin lymphomas respond to chemotherapy and irradiation, but continue to relapse for a long period of time.

X = complete
* = partial
o = optional

Types of Sugery Lymph Chain Splenectomy Other Organs
Excision of tumor mass *
Splenectomy (partial/total/NOS) */X
Lymph node dissection, single chain X
Lymph node dissection, single chain plus splenectomy X X
Lymph node dissection, two or more chains, and/or adjacent organs X *
Lymph node dissection, not otherwise specified X
Lymph node dissection, NOS plus splenectomy X X
Surgery of regional and/or distant sites/nodes X

Surgery for extranodal lymphomas should be described according to the surgical codes for that site.

Key words:

Staging laparotomy—Go to Diagnostic Studies—Pathology for detailed information. Do not code as cancer-directed therapy even if the specimen is diagnosed as positive.