Other Endocrine Glands

In addition to the major endocrine glands, other organs have some hormonal activity as part of their function. These include the thymus, stomach, small intestines, heart, and [glossary term:] placenta.

Thymosin, produced by the thymus gland, plays an important role in the development of the body's immune system.

The lining of the stomach, the gastric mucosa, produces a hormone, called gastrin, in response to the presence of food in the stomach. This hormone stimulates the production of hydrochloric acid and the enzyme pepsin, which are used in the digestion of food.

The mucosa of the small intestine secretes the hormones secretin and [glossary term:] cholecystokinin. Secreting stimulates the pancreas to produce a bicarbonate-rich fluid that neutralizes the stomach acid. [glossary term:] Cholecystokinin stimulates contraction of the gallbladder, which releases bile. It also stimulates the pancreas to secrete digestive enzyme.

The heart also acts as an endocrine organ in addition to its major role of pumping blood. Special cells in the wall of the upper chambers of the heart, called atria, produce a hormone called atrial natriiuretic hormone, or atriopeptin.

The [glossary term:] placenta develops in the pregnant female as a source of nourishment and gas exchange for the developing fetus. It also serves as a temporary endocrine gland. One of the hormones it secretes is human [glossary term:] chorionic [glossary term:] gonadotropin, which signals the mother's ovaries to secrete hormones to maintain the uterine lining so that it does not degenerate and slough off in menstruation.